SCHEMBL20198244

SCHEMBL20198244

[O-][S+](c1ccccc1)c1ccc(-c2ccc(Sc3ccccc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.39
MAOB P27338 3/20 0.39
HPGD P15428 2/20 0.37
ALDH1A1 P00352 2/20 0.37
SLC6A4 P31645 1/20 0.34
MMP3 P08254 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
CHRNA7 P36544 1/20 0.33
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 1/20 0.32
HSD17B10 Q99714 1/20 0.32
BCL2 P10415 1/20 0.32
MCL1 Q07820 1/20 0.32
HTR2C P28335 1/20 0.31
HTR6 P50406 1/20 0.31
NR1H2 P55055 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089982 0.94 MAOA (0.43) MAOAMAOBHPGDALDH1A1SLC6A4
SCHEMBL9275867 0.92 MAOA (0.45) MAOAMAOBHPGDALDH1A1SLC6A4
(Phenylsulfinyl)Benzene SCHEMBL11246408 0.89 MAOA (0.41) MAOAMAOBHPGDALDH1A1SLC6A4
SCHEMBL12336913 0.85 ALDH1A1 (0.42) ALDH1A1MMP3MAPTSMN1; SMN2MGLL
SCHEMBL8772023 0.83 ALDH1A1 (0.47) ALDH1A1MMP3MAPTSMN1; SMN2MGLL
SCHEMBL19103227 0.82 HPGD (0.40) MAOAMAOBHPGDALDH1A1SLC6A4
SCHEMBL2785940 0.80 ALDH1A1 (0.50) ALDH1A1MMP3MAPTSMN1; SMN2MGLL
SCHEMBL9624111 0.80 HTR2C (0.42) MAOAMAOBHPGDALDH1A1SLC6A4
SCHEMBL2754909 0.80 MAOA (0.54) MAOAMAOBHPGDALDH1A1SLC6A4
SCHEMBL10705269 0.80 MAOA (0.54) MAOAMAOBHPGDALDH1A1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675930-B1 NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2018-05-30 EP disclosed