SCHEMBL20198427

SCHEMBL20198427

C/C=C\C(=C/CC)c1ccc2c(F)cccc2n1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.34
CYSLTR2 Q9NS75 1/20 0.33
CYSLTR1 Q9Y271 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PDE7A Q13946 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19752270 0.81 PDE10A (0.33) PDE10AMEN1KMT2A
SCHEMBL21974364 0.69 PDE10A (0.32) PDE10AMEN1KMT2A
SCHEMBL18463728 0.69 PDE10A (0.37) PDE10ACYSLTR2CYSLTR1MEN1KMT2A
SCHEMBL6193849 0.69 MGAM (0.56) MEN1KMT2A
SCHEMBL19752309 0.66 CYP2D6 (0.35)
SCHEMBL21217565 0.66 SCN9A (0.44)
SCHEMBL13668629 0.66 PDE10A (0.47) PDE10ACYSLTR2CYSLTR1MEN1KMT2A
Lithium Ion SCHEMBL5149555 0.65 MGAM (0.40) CYSLTR2CYSLTR1MEN1KMT2A
SCHEMBL20748672 0.65
SCHEMBL22600767 0.65 ATM (0.41) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 EP disclosed
EP-3327100-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2018-05-30 EP disclosed