Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193849 | 0.84 | MGAM (0.56) | MGAMGRM2CNR2MEN1KMT2A | |
| SCHEMBL3207562 | 0.77 | ALDH1A1 (0.46) | MGAMGRM2CNR2CYP1A2MEN1 | |
| SCHEMBL18463728 | 0.75 | PDE10A (0.37) | MGAMGRM2HSD17B14MEN1KMT2A | |
| Quinaldic Acid SCHEMBL359790 | 0.73 | MGAM (0.66) | MGAMCNR2CYP1A2CYP2C9MEN1 | |
| SCHEMBL31756394 | 0.71 | PDE7A (0.36) | CYP1A2MEN1KMT2A | |
| SCHEMBL12144700 | 0.70 | COPS5 (0.45) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL6664318 | 0.70 | ADORA2A (0.38) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| Quinaldic Acid SCHEMBL5463662 | 0.69 | MGAM (0.66) | MGAMCNR2CYP1A2CYP2C9MEN1 | |
| Quinaldic Acid SCHEMBL4587205 | 0.69 | MGAM (0.66) | MGAMCNR2CYP1A2CYP2C9MEN1 | |
| Quinaldic Acid SCHEMBL16735544 | 0.69 | MGAM (0.66) | MGAMCNR2CYP1A2CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070200096-A1 | Doped lithium quinolate | OLED-T LIMITED (GB) | 2007-08-30 | — | — | US | claimed |