Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.61 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.61 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424069 | 0.87 | LMNA (0.71) | MAPTSRPK1NPSR1ALDH1A1TSHR | |
| SCHEMBL8274190 | 0.82 | MAPT (0.70) | MAPTKDRSRPK2SRPK1SRPK3 | |
| SCHEMBL12765700 | 0.82 | KDR (0.60) | MAPTKDRSRPK2SRPK1SRPK3 | |
| SCHEMBL1110612 | 0.80 | SRPK1 (0.77) | MAPTKDRSRPK2SRPK1SRPK3 | |
| SCHEMBL1110601 | 0.80 | ALDH1A1 (0.71) | MAPTKDRSRPK2SRPK1SRPK3 | |
| SCHEMBL1110549 | 0.80 | ALDH1A1 (0.71) | MAPTKDRSRPK2SRPK1SRPK3 | |
| SCHEMBL1110637 | 0.79 | NPSR1 (0.69) | MAPTKDRSRPK2SRPK1SRPK3 | |
| SCHEMBL13763653 | 0.79 | MAPT (0.74) | MAPTKDRSRPK2SRPK1SRPK3 | |
| SCHEMBL1110749 | 0.78 | MAPT (0.53) | MAPTKDRSRPK2SRPK1SRPK3 | |
| SCHEMBL12765702 | 0.78 | ALDH1A1 (0.65) | MAPTKDRSRPK2SRPK1SRPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1712242-B1 | METHOD OF REGULATING PHOSPHORYLATION OF SR PROTEIN AND ANTIVIRAL AGENTS COMPRISING SR PROTEIN ACTIVITY REGULATOR AS THE ACTIVE INGREDIENT | HAGIWARA MASATOSHI (JP) | 2018-05-30 | — | — | EP | disclosed |