SCHEMBL20198539

SCHEMBL20198539

CC(C)=C(C)NC(=O)c1cccc(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.57
CYP2C19 P33261 2/20 0.57
CYP3A4 P08684 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.55
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
MTOR P42345 3/20 0.55
OGG1 O15527 2/20 0.54
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
ALDH1A1 P00352 1/20 0.51
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
AGTR1 P30556 1/20 0.50
OPRK1 P41145 1/20 0.50
PARP1 P09874 1/20 0.50
GRM5 P41594 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265872 0.82 HDAC8 (0.69) CYP1A2CYP2C19CYP3A4L3MBTL1SMN1; SMN2
SCHEMBL17336679 0.80 SMN1; SMN2 (0.64) CYP1A2CYP2C19CYP3A4L3MBTL1SMN1; SMN2
SCHEMBL17236166 0.77 SMN1; SMN2 (0.77) CYP1A2CYP2C19L3MBTL1SMN1; SMN2NPC1
Ammonia Solution, Strong SCHEMBL27841907 0.77 PARP1 (0.61) CYP1A2CYP2C19CYP3A4L3MBTL1SMN1; SMN2
SCHEMBL31305679 0.77 KDM4E (0.64) L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL17336774 0.77 KDM4E (0.64) L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL10347754 0.77 ALDH1A1 (0.55) CYP1A2L3MBTL1SMN1; SMN2NPC1RAB9A
SCHEMBL7377540 0.77 SMN1; SMN2 (0.67) CYP1A2CYP2C19L3MBTL1SMN1; SMN2NPC1
SCHEMBL27638931 0.77 L3MBTL1 (0.54) CYP1A2CYP2C19CYP3A4L3MBTL1SMN1; SMN2
SCHEMBL3169 0.75 PARP1 (0.63) CYP1A2CYP2C19CYP3A4L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496591-B1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2018-05-30 EP disclosed