SCHEMBL20198598

SCHEMBL20198598

C1=CC23CCCCC(CC2)(N3)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OXTR P30559 1/20 0.36
PDE7A Q13946 1/20 0.35
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
OPRM1 P35372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23740124 0.98 PDE7A (0.37) OXTRPDE7A
SCHEMBL20104727 0.83 PDE7A (0.38) OXTRPDE7A
SCHEMBL20104729 0.83 PDE7A (0.38) OXTRPDE7A
SCHEMBL30817704 0.70 PDE7A (0.41) OXTRPDE7A
SCHEMBL20198617 0.70 PDE7A (0.36) PDE7A
SCHEMBL20198618 0.70 PDE7A (0.36) PDE7A
SCHEMBL3923960 0.69 OXTR (0.49) OXTR
SCHEMBL3847169 0.68 HTR2C (0.35) OXTRPDE7AHTR2CHTR2B
SCHEMBL20198627 0.67 PDE7A (0.44) PDE7A
SCHEMBL23740301 0.67 PDE7A (0.44) PDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3327603-A1 METHOD AND DEVICE FOR CALCULATING ACID DISSOCIATION CONSTANT, AND PROGRAM Fujitsu Limited (JP) 2018-05-30 EP disclosed