SCHEMBL20104727

SCHEMBL20104727

C1=CC23CCCCCCCC(C2)(N3)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 7/20 0.38
OXTR P30559 1/20 0.36
PDE7B Q9NP56 1/20 0.32
ACAT2 Q9BWD1 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20104729 1.00 PDE7A (0.38) PDE7AOXTRPDE7BACAT2LMNA
SCHEMBL23740124 0.85 PDE7A (0.37) PDE7AOXTRPDE7BACAT2LMNA
SCHEMBL20198598 0.83 OXTR (0.36) PDE7AOXTR
SCHEMBL30817704 0.74 PDE7A (0.41) PDE7AOXTRPDE7BACAT2LMNA
SCHEMBL20104700 0.71 PDE7A (0.36) PDE7APDE7B
SCHEMBL20104744 0.71 PDE7A (0.44) PDE7APDE7BLMNAPOLB
SCHEMBL24505981 0.71 OXTR (0.48) OXTR
SCHEMBL6914407 0.70 MAPT (0.43) PDE7AACAT2LMNAPOLB
SCHEMBL3923960 0.69 OXTR (0.49) OXTR
SCHEMBL7825051 0.66 LMNA (0.33) LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11195597-B2 Method and device for calculating acid dissociation constant, and program FUJITSU LIMITED (JP) 2021-12-07 US disclosed
EP-3327603-B1 METHOD AND DEVICE FOR CALCULATING ACID DISSOCIATION CONSTANT, AND PROGRAM FUJITSU LTD (JP) 2021-08-11 EP disclosed
EP-3327603-A1 METHOD AND DEVICE FOR CALCULATING ACID DISSOCIATION CONSTANT, AND PROGRAM Fujitsu Limited (JP) 2018-05-30 EP disclosed
US-20180121632-A1 METHOD AND DEVICE FOR CALCULATING ACID DISSOCIATION CONSTANT, AND PROGRAM FUJITSU LIMITED (JP) 2018-05-03 US disclosed