Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.54 |
| ▸ | NQO2 | P16083 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103988 | 0.88 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2MCL1TRPV1 | |
| Bromide SCHEMBL7245774 | 0.87 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2MCL1TRPV1 | |
| Hydrochloric Acid SCHEMBL15661933 | 0.87 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2MCL1TRPV1 | |
| SCHEMBL26061042 | 0.85 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2MCL1TRPV1 | |
| SCHEMBL26059358 | 0.83 | CYP3A4 (0.57) | MTNR1AMTNR1BNQO2MCL1TRPV1 | |
| SCHEMBL8020797 | 0.81 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2TLR8TRPV1 | |
| SCHEMBL12676044 | 0.81 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2MCL1TRPV1 | |
| SCHEMBL11586989 | 0.80 | TLR8 (0.51) | MTNR1ATLR8HTR2ACYP1A2CYP3A4 | |
| SCHEMBL30301302 | 0.79 | SLC6A4 (0.51) | MTNR1ANQO2TLR8CYP1A2CYP2D6 | |
| SCHEMBL131656 | 0.79 | SLC6A4 (0.51) | MTNR1ANQO2TLR8CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885366-B1 | PHARMACOLOGICAL CHAPERONES FOR TREATING OBESITY | AMICUS THERAPEUTICS INC (US) | 2018-05-30 | — | — | EP | disclosed |