Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22893332 | 0.92 | MAPT (0.40) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| SCHEMBL22893206 | 0.92 | MAPT (0.40) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| SCHEMBL341087 | 0.80 | MAPT (0.54) | MAPTGAACES1P2RX4RAB9A | |
| SCHEMBL22893207 | 0.74 | MAPT (0.47) | MAPTGAACES1P2RX4RAB9A | |
| SCHEMBL6279537 | 0.70 | MAPT (0.50) | MAPTGAASMN1; SMN2MAOAMAOB | |
| SCHEMBL6358112 | 0.70 | MAPT (0.50) | MAPTGAASMN1; SMN2MAOAMAOB | |
| SCHEMBL15705869 | 0.70 | MAPT (0.46) | MAPTGAACES1P2RX4RAB9A | |
| Iminostilbene SCHEMBL75288 | 0.67 | MAPT (1.00) | MAPTGAACES1P2RX4RAB9A | |
| Iminostilbene SCHEMBL29926907 | 0.67 | MAPT (1.00) | MAPTGAACES1P2RX4RAB9A | |
| SCHEMBL4459200 | 0.67 | MAPT (0.46) | MAPTGAAP2RX4RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327488-B1 | OPTICAL ARTICLE COMPRISING A DYE RESISTANT TO PHOTO-DEGRADATION | ESSILOR INT (FR) | 2021-01-06 | — | — | EP | disclosed |
| WO-2018095671-A1 | OPTICAL ARTICLE COMPRISING A DYE RESISTANT TO PHOTO-DEGRADATION | ESSILOR INTERNATIONAL (FR) | 2018-05-31 | — | — | WO | disclosed |
| EP-3327488-A1 | OPTICAL ARTICLE COMPRISING A DYE RESISTANT TO PHOTO-DEGRADATION | Essilor International (FR) | 2018-05-30 | — | — | EP | disclosed |