SCHEMBL341087

SCHEMBL341087

O=C1C(=C2C=Cc3ccccc3N2)C(=O)c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.54
GAA P10253 2/20 0.54
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
POLB P06746 4/20 0.42
LMNA P02545 4/20 0.42
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 3/20 0.42
MAOA P21397 2/20 0.42
BCHE P06276 2/20 0.42
PTPRC P08575 2/20 0.42
THRB P10828 2/20 0.42
CES1 P23141 2/20 0.42
RECQL P46063 2/20 0.42
ALOX15 P16050 2/20 0.42
IDO1 P14902 2/20 0.42
PKM P14618 2/20 0.42
MAOB P27338 1/20 0.42
PTPN1 P18031 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15705869 0.89 MAPT (0.46) MAPTGAAMEN1KMT2APOLB
SCHEMBL10053806 0.82 CSNK1G1 (0.47) MAPTGAAMEN1KMT2APOLB
SCHEMBL6358112 0.82 MAPT (0.50) MAPTGAALMNAALDH1A1KDM4E
SCHEMBL6279537 0.82 MAPT (0.50) MAPTGAALMNAALDH1A1KDM4E
SCHEMBL22893207 0.80 MAPT (0.47) MAPTGAAMEN1KMT2APOLB
SCHEMBL20198694 0.80 MAPT (0.47) MAPTGAAMEN1KMT2APOLB
SCHEMBL31297139 0.79 TTR (0.49) MAPTGAAMEN1KMT2APOLB
SCHEMBL2121518 0.77 PGAM1 (0.38) MAPTGAAMEN1KMT2APOLB
SCHEMBL16478893 0.75 STAT3 (0.38) MAPTMEN1KMT2APOLBLMNA
SCHEMBL16473097 0.75 MAPT (0.36) MAPTGAAMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296901-B2 Composite particles, and coloring composition and resin composition using the same TODA KOGYO CORPORATION (JP) 2016-03-29 US claimed
US-20150079008-A1 FLUORESCENCE PLAQUE-DISCLOSANT FOR DETECTING DENTAL PLAQUE FLOSS MY HEART, LLC 2015-03-19 US claimed
EP-2099869-B1 MODIFIED PIGMENTS AND METHODS FOR MAKING AND USING THE SAME SENSIENT COLORS INC (US) 2013-05-01 EP claimed
US-20100081728-A1 Mixable and color tone freely reproducible dental coloring material composition, and set and method thereof KABUSHIKI KAISHA SHOFU 2010-04-01 US claimed
EP-1929304-A2 CELLULAR OR ORGANELLE-ENTRAPPED NANOPARTICLES Freedom-2, LLC (US) 2008-06-11 EP claimed
WO-2007024429-A2 CELLULAR OR ORGANELLE-ENTRAPPED NANOPARTICLES FREEDOM-2, LLC (US) 2007-03-01 WO claimed
US-20060050946-A1 Computer-assisted cell analysis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-03-09 US claimed
US-6106852-A Temporary tattoo device and method DELIQUESCENCE HOLDINGS, INC. (CA) 2000-08-22 US claimed
WO-1999012753-A1 DEVICE AND METHOD FOR APPLYING A TEMPORARY TATTOO DELIQUESCENCE HOLDINGS INC. (CA) 1999-03-18 WO claimed
EP-4748891-A1 RUBBER COMPOSITION NOK Corporation (JP) 2026-05-27 EP disclosed
US-12558205-B2 Composition for forming artificial tooth, method of preparing artificial tooth, and artificial tooth prepared thereby ODS CO., LTD. (KR) 2026-02-24 US disclosed
US-20260048043-A1 HIGH LOADING ORAL FILM FORMULATION WITH IMPROVED BIOAVAILABILITY INTELGENX CORP (CA) 2026-02-19 US disclosed
EP-4308135-B1 THERAPEUTIC USE OF ENGINEERED POSTBIOTICS COMPRISING BACTERIOCINS AND/OR ENDOLYSINS ELIGO BIOSCIENCE (FR) 2025-12-03 EP disclosed
US-20250216301-A1 DEVICES AND METHODS FOR TISSUE AND CELL STAINING (II) ESSENLIX CORPORATION (US) 2025-07-03 US disclosed
US-4952401-A Rodenticide for toxic wick ICI AMERICAS INC. (US) 1990-08-28 US disclosed
US-4868206-A LIQUID, HYDROXYCOUMARIN DERIVATIVES ICI AMERICAS INC. (US) 1989-09-19 US disclosed
US-4855133-A Composition for attracting flies EARTH CHEMICAL COMPANY, LIMITED (JP) 1989-08-08 US disclosed
EP-0316054-A1 Cosmetic containing fine soft microcapsules SHISEIDO COMPANY LIMITED (JP) 1989-05-17 EP disclosed
EP-0225795-A2 Composition for rodent control ICI AMERICAS INC. (US) 1987-06-16 EP disclosed
US-4169169-A DECALS FOR SKIN, ALCOHOL SOLUBLE DYES DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1979-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558205-B2 Composition for forming artificial tooth, method of preparing artificial tooth, and artificial tooth prepared thereby PFN1, GPX1, TFAM MAPT 718/4885GAA 3964/4885MEN1 4628/4885
US-20260048043-A1 HIGH LOADING ORAL FILM FORMULATION WITH IMPROVED BIOAVAILABILITY MUC1, TAS2R42, MTX2 MAPT 2009/4885GAA 3347/4885MEN1 1264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.