Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2028001 | 1.00 | — | — | |
| Sulfuric Acid SCHEMBL38652093 | 0.95 | CA5A (0.55) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL15510691 | 0.95 | CA5A (0.55) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL5583868 | 0.95 | CA5A (0.55) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL1457810 | 0.95 | CA5A (0.55) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL11767576 | 0.95 | CA5A (0.55) | CA5ACA5BTSHRCA2CA1 | |
| Sulfuric Acid SCHEMBL27892057 | 0.89 | — | — | |
| Phosphoric Acid SCHEMBL15536850 | 0.84 | CA5A (0.43) | CA5ACA5BBLMKDM4ECYP2D6 | |
| Sulfuric Acid SCHEMBL15510902 | 0.84 | CA5A (0.43) | CA5ACA5BBLMKDM4ECYP2D6 | |
| Sulfuric Acid SCHEMBL28431118 | 0.84 | CA5A (0.43) | CA5ACA5BBLMKDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9649372-B2 | Immunogenic compositions and related methods | SANOFI PASTEUR LIMITED (CA) | 2017-05-16 | — | — | US | disclosed |
| US-9649372-B2 | Immunogenic compositions and related methods | SANOFI PASTEUR LIMITED (CA) | 2017-05-16 | — | — | US | disclosed |
| CN-102939105-A | Immunogenic compositions and related methods | SANOFI PASTEUR LTD | 2013-02-20 | — | — | CN | disclosed |
| US-20130034579-A1 | IMMUNOGENIC COMPOSITIONS AND RELATED METHODS | SANOFI PASTEUR LIMITED (CA) | 2013-02-07 | — | — | US | disclosed |
| US-20130034579-A1 | IMMUNOGENIC COMPOSITIONS AND RELATED METHODS | SANOFI PASTEUR LIMITED (CA) | 2013-02-07 | — | — | US | disclosed |
| EP-2515940-A1 | IMMUNOGENIC COMPOSITIONS AND RELATED METHODS | Sanofi Pasteur Limited (CA) | 2012-10-31 | — | — | EP | disclosed |
| EP-2515940-A1 | IMMUNOGENIC COMPOSITIONS AND RELATED METHODS | Sanofi Pasteur Limited (CA) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011075822-A8 | IMMUNOGENIC COMPOSITIONS AND RELATED METHODS | SANOFI PASTEUR LIMITED (CA) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011075822-A1 | IMMUNOGENIC COMPOSITIONS AND RELATED METHODS | SANOFI PASTEUR LIMITED (CA) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011075822-A1 | IMMUNOGENIC COMPOSITIONS AND RELATED METHODS | SANOFI PASTEUR LIMITED (CA) | 2011-06-30 | — | — | WO | disclosed |