Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20175023 | 0.95 | PLA2G2A (0.32) | PLA2G2APLA2G4APLA2G10PDK2 | |
| SCHEMBL20175231 | 0.94 | PDK2 (0.33) | PLA2G2APLA2G4APDK2ALOX5 | |
| SCHEMBL22326529 | 0.93 | PLA2G2A (0.39) | PLA2G2APLA2G4APLA2G10PDK2ALOX5 | |
| SCHEMBL20198963 | 0.92 | PDK2 (0.30) | PDK2 | |
| SCHEMBL20175007 | 0.92 | PDK2 (0.34) | PLA2G2APLA2G4APLA2G10PDK2 | |
| SCHEMBL20175024 | 0.92 | PDK2 (0.34) | PLA2G2APLA2G4APLA2G10PDK2 | |
| SCHEMBL20174976 | 0.91 | PDK2 (0.30) | PLA2G2APLA2G4APDK2 | |
| SCHEMBL20174788 | 0.91 | PDK2 (0.36) | PLA2G2APLA2G4APLA2G10PDK2ALOX5 | |
| SCHEMBL20198961 | 0.91 | PDK2 (0.36) | PLA2G2APLA2G4APLA2G10PDK2ALOX5 | |
| SCHEMBL23592407 | 0.91 | PLA2G2A (0.34) | PLA2G2APLA2G4APLA2G10CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781366-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-09-22 | — | — | US | disclosed |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10781366-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | PLA2G2A 4788/4885PLA2G4A 4802/4885PLA2G10 4732/4885 |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | PLA2G2A 4788/4885PLA2G4A 4802/4885PLA2G10 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.