Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12574514 | 0.80 | GAA (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL223674 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1079274 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1081864 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL23582744 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3935286 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL753436 | 0.70 | ALDH1A1 (0.42) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1712315 | 0.70 | ALDH1A1 (0.37) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL23582300 | 0.69 | ALDH1A1 (0.36) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14556270 | 0.69 | HIF1A (0.39) | ALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315224-B | Cyclopentylacrylic acid amide derivative | 杏林制药株式会社 | 2018-04-10 | — | — | CN | disclosed |
| US-9452977-B2 | Cyclopentylacrylamide derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-9452977-B2 | Cyclopentylacrylamide derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2016-09-27 | — | — | US | disclosed |
| CN-102089291-B | Cyclopentyl acrylamide derivative | 杏林制药株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-105315224-A | Cyclopentylacrylamide derivative | KYORIN SEIYAKU KK | 2016-02-10 | — | — | CN | disclosed |
| EP-2275414-B1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | KYORIN SEIYAKU KK (JP) | 2015-06-10 | — | — | EP | disclosed |
| US-20150105581-A1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | TEIJIN LIMITED (JP) | 2015-04-16 | — | — | US | disclosed |
| US-20150105581-A1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | TEIJIN LIMITED (JP) | 2015-04-16 | — | — | US | disclosed |
| US-8946440-B2 | Cyclopentylacrylamide derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-8946440-B2 | Cyclopentylacrylamide derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-20110160211-A1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | TEIJIN LIMITED (JP) | 2011-06-30 | — | — | US | disclosed |
| US-20110160211-A1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | TEIJIN LIMITED (JP) | 2011-06-30 | — | — | US | disclosed |
| CN-102089291-A | Cyclopentyl acrylamide derivative | TEIJIN PHARMA LTD | 2011-06-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160211-A1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | GPR119, SLC5A1, SLC5A2 | ALDH1A1 606/4885TDP1 4684/4885MEN1 2643/4885 |
| US-20150105581-A1 | CYCLOPENTYLACRYLAMIDE DERIVATIVE | GPR119, SLC5A1, SLC5A2 | ALDH1A1 606/4885TDP1 4684/4885MEN1 2643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.