Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22403174 | 0.91 | BCL9 (0.48) | BCL9CTNNB1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL20189160 | 0.90 | BCL9 (0.47) | BCL9CTNNB1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL22112107 | 0.89 | BCL9 (0.43) | BCL9CTNNB1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL20200104 | 0.89 | BCL9 (0.42) | BCL9CTNNB1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL20199816 | 0.87 | ALDH1A1 (0.50) | BCL9CTNNB1SMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL20199841 | 0.85 | BCL9 (0.44) | BCL9CTNNB1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL20199980 | 0.83 | ACHE (0.41) | BCL9CTNNB1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL22112586 | 0.83 | ALDH1A1 (0.47) | BCL9CTNNB1SMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL20199801 | 0.82 | ACHE (0.42) | BCL9CTNNB1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL22403270 | 0.81 | BCL9 (0.42) | BCL9CTNNB1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544964-B1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma AG (DE) | 2020-06-17 | — | — | EP | disclosed |
| WO-2018096082-A1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | WO | disclosed |