Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187503 | 0.95 | PLA2G10 (0.36) | PLA2G10PLA2G5MEN1KMT2ANPC1 | |
| SCHEMBL20199970 | 0.82 | CA12 (0.33) | PLA2G10PLA2G5MEN1KMT2AALDH1A1 | |
| SCHEMBL18365256 | 0.82 | KMT2A (0.41) | PLA2G10PLA2G5MEN1KMT2AALDH1A1 | |
| SCHEMBL29341696 | 0.82 | KMT2A (0.41) | PLA2G10PLA2G5MEN1KMT2AALDH1A1 | |
| SCHEMBL22112086 | 0.79 | PLA2G10 (0.39) | PLA2G10PLA2G5MEN1KMT2ANPC1 | |
| SCHEMBL22393528 | 0.78 | CYP1A2 (0.47) | PLA2G10PLA2G5MEN1KMT2AALDH1A1 | |
| SCHEMBL20187582 | 0.77 | KDM4E (0.41) | PLA2G10PLA2G5MEN1KMT2ANPC1 | |
| SCHEMBL20187581 | 0.76 | ALDH1A1 (0.36) | PLA2G10PLA2G5MEN1KMT2ANPC1 | |
| SCHEMBL20187535 | 0.76 | PLA2G10 (0.35) | PLA2G10PLA2G5MEN1KMT2ANPC1 | |
| SCHEMBL12292937 | 0.76 | SIGMAR1 (0.38) | PLA2G10PLA2G5MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096082-A1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | WO | disclosed |