Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cyclohexane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL8006197 | 1.00 | CA5A (0.73) | CA5ACA5BMEN1KMT2AGSR | |
| Nitric Acid SCHEMBL7750558 | 0.85 | — | — | |
| Nitric Acid SCHEMBL234 | 0.85 | — | — | |
| Nitric Acid SCHEMBL28411161 | 0.85 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL37356 | 0.85 | — | — | |
| Nitric Acid SCHEMBL302522 | 0.85 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL10981408 | 0.85 | — | — | |
| Nitric Acid SCHEMBL3762342 | 0.85 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL8383283 | 0.85 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL8547 | 0.85 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118147680-A | Electrocatalytic system for continuously producing adipic acid by taking lignin phenol derivatives as raw materials and method for preparing adipic acid by using electrocatalytic system | 中国科学院理化技术研究所 | 2024-06-07 | — | — | CN | disclosed |
| CN-111253281-B | Preparation method of cyclohexanone oxime | 湘潭大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-109761793-B | Method for separating and purifying mixed dibasic acid by solution-melt crystallization coupling | 河北工业大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-113200842-A | Adipic acid preparation method and system | 中石油吉林化工工程有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-112149930-A | Method for determining nitrous oxide emission in adipic acid production process | 苏州五蕴明泰科技有限公司 | 2020-12-29 | — | — | CN | disclosed |
| EP-3344620-A1 | 1-(4-(2-((1-(3,4-DIFLUOROPHENYL)-1H-PYRAZOL-3-YL)METHOXY)ETHYL) PIPERAZIN-1-YL)ETHANONE SALTS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017037166-A1 | 1-(4-(2-((1-(3,4-DIFLUOROPHENYL)-1H-PYRAZOL-3-YL)METHOXY)ETHYL) PIPERAZIN-1-YL)ETHANONE SALTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2017-03-09 | — | — | WO | disclosed |
| EP-2516379-B1 | HYDROCARBON FEED FLEXIBLE HIGH PRESSURE NITRATION PLANT DESIGN | ANGUS CHEMICAL (US) | 2016-12-28 | — | — | EP | disclosed |
| US-9504933-B2 | Hydrocarbon feed flexible high pressure nitration plant design | ANGUS CHEMICAL COMPANY (US) | 2016-11-29 | — | — | US | disclosed |
| US-20130343960-A1 | HYDROCARBON FEED FLEXIBLE HIGH PRESSURE NITRATION PLANT DESIGN | ANGUS CHEMICAL COMPANY (US) | 2013-12-26 | — | — | US | disclosed |
| US-8558039-B2 | Hydrocarbon feed flexible high pressure nitration plant design | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-10-15 | — | — | US | disclosed |
| CN-102040735-B | Aspartic acid-cyclodextrin copolymer and intermediate polymer, preparation methods of same as well as application thereof | UNIV EAST CHINA SCIENCE & TECH | 2013-06-19 | — | — | CN | disclosed |
| EP-2516379-A1 | HYDROCARBON FEED FLEXIBLE HIGH PRESSURE NITRATION PLANT DESIGN | Dow Global Technologies LLC (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20110160496-A1 | HYDROCARBON FEED FLEXIBLE HIGH PRESSURE NITRATION PLANT DESIGN | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-06-30 | — | — | US | disclosed |
| WO-2011078931-A1 | HYDROCARBON FEED FLEXIBLE HIGH PRESSURE NITRATION PLANT DESIGN | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-06-30 | — | — | WO | disclosed |
| CN-102040735-A | Aspartic acid-cyclodextrin copolymer and intermediate polymer, preparation methods of aspartic acid-cyclodextrin copolymer and intermediate polymer as well as application of aspartic acid-cyclodextrin copolymer | UNIV EAST CHINA SCIENCE & TECH | 2011-05-04 | — | — | CN | disclosed |