SCHEMBL2020071

SCHEMBL2020071

OCCC[C]1CCCCC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599324 1.00 CA2 (0.30) CA2
SCHEMBL4598997 0.97
SCHEMBL4599047 0.92
SCHEMBL2945407 0.85
SCHEMBL4598920 0.82
SCHEMBL6607326 0.82 CA2 (0.32) CA2
SCHEMBL10490386 0.82 CYP1A2 (0.33)
SCHEMBL6055461 0.80 CA2 (0.31) CA2
SCHEMBL9647392 0.79
SCHEMBL21085042 0.74 CHRM1 (0.36) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372854-B2 Pyrrolo[2,3-D]pyrimidine compounds PFIZER INC. (US) 2013-02-12 US claimed
EP-2513114-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS Pfizer Inc. (US) 2012-10-24 EP claimed
US-20110294826-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS PFIZER INC. (US) 2011-12-01 US claimed
WO-2011075334-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS PFIZER INC. (US) 2011-06-23 WO claimed
US-8372854-B2 Pyrrolo[2,3-D]pyrimidine compounds PFIZER INC. (US) 2013-02-12 US disclosed
CN-101974120-B Nano-crystalline silicon containing deep ultraviolet negative amplification type photoresist and film forming resin thereof KUNSHAN XIDI ELECTRO OPTIC MATERIALS CO LTD 2012-12-26 CN disclosed
EP-2513114-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS Pfizer Inc. (US) 2012-10-24 EP disclosed
CN-101974119-B Nano silicon containing deep ultraviolet positive photoresist and forming resin thereof KUNSHAN XIDI ELECTRO OPTIC MATERIALS CO LTD 2012-10-03 CN disclosed
CN-102050946-B Ultraviolet positive photoresist containing nano silicon polyamide and film-forming resin thereof KUNSHAN XIDI OPTOELECTRONIC MATERIAL CO LTD 2012-06-27 CN disclosed
CN-101979435-B Nanometer silicon-containing ultraviolet thick film positive photoresist and film forming resin thereof KUNSHAN XIDI PHOTOELECTRIC MATERIAL CO LTD 2012-05-30 CN disclosed
US-20110294826-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS PFIZER INC. (US) 2011-12-01 US disclosed
WO-2011075334-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS PFIZER INC. (US) 2011-06-23 WO disclosed
CN-102050946-A Ultraviolet positive photoresist containing nano silicon polyamide and film-forming resin thereof KUNSHAN XIDI OPTOELECTRONIC MATERIAL CO LTD 2011-05-11 CN disclosed
CN-101979435-A Nanometer silicon-containing ultraviolet thick film positive photoresist and film forming resin thereof KUNSHAN XIDI PHOTOELECTRIC MATERIAL CO LTD 2011-02-23 CN disclosed
CN-101974119-A Nano silicon containing deep ultraviolet positive photoresist and forming resin thereof KUNSHAN XIDI ELECTRO OPTIC MATERIALS CO LTD 2011-02-16 CN disclosed
CN-101974120-A Nano-crystalline silicon containing deep ultraviolet negative amplification type photoresist and film forming resin thereof KUNSHAN XIDI ELECTRO OPTIC MATERIALS CO LTD 2011-02-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294826-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS JAK3, JAK1, JAK2 CA2 4214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.