Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 19/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20200769 | 0.81 | APLNR (0.41) | APLNRNPC1ALDH1A1 | |
| SCHEMBL20201117 | 0.81 | APLNR (0.42) | APLNRNPC1ALDH1A1 | |
| SCHEMBL20201071 | 0.80 | APLNR (0.57) | APLNR | |
| SCHEMBL20201129 | 0.78 | APLNR (0.42) | APLNR | |
| SCHEMBL20200894 | 0.76 | ALDH1A1 (0.49) | APLNRNPC1ALDH1A1 | |
| SCHEMBL20201084 | 0.76 | APLNR (0.47) | APLNR | |
| SCHEMBL20201134 | 0.75 | APLNR (0.51) | APLNR | |
| SCHEMBL21339359 | 0.74 | APLNR (0.46) | APLNR | |
| SCHEMBL21339423 | 0.73 | APLNR (0.45) | APLNR | |
| SCHEMBL20201110 | 0.73 | APLNR (0.49) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097944-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |