SCHEMBL20201503

SCHEMBL20201503

CCCCCN1CCN(S(=O)(=O)CC)CC1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 6/20 0.52
GNAO1 P09471 6/20 0.52
GNAI1 P63096 6/20 0.52
THRB P10828 9/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20376410 0.86 HRH2 (0.52) GNAI3GNAO1GNAI1
SCHEMBL2942714 0.86 GNAI3 (0.55) GNAI3GNAO1GNAI1
SCHEMBL10263618 0.85 MEN1 (0.47) THRB
SCHEMBL38665905 0.84 GNAI3 (0.53) GNAI3GNAO1GNAI1
SCHEMBL4363929 0.83 SMN1; SMN2 (0.41) THRB
SCHEMBL250855 0.82 GNAI3 (0.70) GNAI3GNAO1GNAI1
SCHEMBL35895 0.82
SCHEMBL1043043 0.82 GNAI3 (0.70) GNAI3GNAO1GNAI1
SCHEMBL4363932 0.82 SMN1; SMN2 (0.43) THRB
SCHEMBL20204622 0.81 HRH2 (0.55) GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018098206-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed