Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201503 | 0.81 | GNAI3 (0.52) | GNAI3GNAO1GNAI1 | |
| SCHEMBL2942714 | 0.79 | GNAI3 (0.55) | HRH2HRH1GNAI3GNAO1GNAI1 | |
| SCHEMBL20376410 | 0.79 | HRH2 (0.52) | HRH2HRH1GNAI3GNAO1GNAI1 | |
| SCHEMBL17404867 | 0.79 | HRH2 (0.42) | HRH2HRH1 | |
| SCHEMBL8443212 | 0.79 | POLB (0.41) | HRH2HRH1 | |
| SCHEMBL25013400 | 0.78 | ALDH1A1 (0.47) | HRH2HRH1KDM4EGAA | |
| SCHEMBL38665905 | 0.78 | GNAI3 (0.53) | HRH2HRH1GNAI3GNAO1GNAI1 | |
| SCHEMBL13100462 | 0.76 | — | — | |
| SCHEMBL1043043 | 0.76 | GNAI3 (0.70) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL250855 | 0.76 | GNAI3 (0.70) | GNAI3GNAO1GNAI1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |