Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076893 | 0.87 | ADRB2 (0.54) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL17277526 | 0.85 | ADRB2 (0.52) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL17277322 | 0.85 | ADRB2 (0.52) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL1496742 | 0.83 | ADRB2 (0.66) | ADRB2ADRB1KMT2AMEN1L3MBTL1 | |
| SCHEMBL20207606 | 0.82 | ADRB2 (0.56) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL10154613 | 0.82 | ADRB2 (0.56) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL17425093 | 0.80 | LMNA (0.53) | ADRB2ADRB1 | |
| SCHEMBL27523668 | 0.79 | ADRB2 (0.50) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| SCHEMBL3723068 | 0.78 | ADRB2 (0.59) | ADRB2ADRB1ACHEKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL27537979 | 0.78 | ADRB2 (0.49) | ADRB2ADRB1ACHEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098208-A1 | NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |