Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 9/20 | 0.36 |
| ▸ | HTR2A | P28223 | 8/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207828 | 0.72 | SCN9A (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL26179883 | 0.68 | HTR2A (0.39) | HTR2CHTR2AHTR2BMAOA | |
| SCHEMBL18590584 | 0.67 | KDM1A (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL17269813 | 0.67 | KDM4E (0.39) | HTR2CHTR2AHTR2B | |
| SCHEMBL20201610 | 0.67 | ADRA1A (0.36) | — | |
| SCHEMBL20376449 | 0.67 | ADRA1A (0.36) | — | |
| SCHEMBL20015310 | 0.66 | MAOB (0.54) | MAOBHTR2CHTR2ASLC6A4 | |
| SCHEMBL18374089 | 0.66 | MAOB (0.40) | MAOBHTR2CHTR2AMAOASLC6A4 | |
| SCHEMBL8153366 | 0.66 | HTR2A (0.56) | HTR2CHTR2ASLC6A4 | |
| SCHEMBL21019437 | 0.65 | HTR2A (0.42) | MAOBHTR2CHTR2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |