SCHEMBL20201642

SCHEMBL20201642

Cc1ccc(N(c2ccc(-c3ccc(N(c4ccc(-c5ccc(N(c6cccc(C)c6)c6cccc(C)c6)cc5)cc4)c4ccc(-c5ccc(N(c6cccc(C)c6)c6cccc(C)c6)cc5)cc4)cc3)cc2)c2cccc(C)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 5/20 0.45
HSD17B2 P37059 5/20 0.45
ACHE P22303 3/20 0.42
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TP53 P04637 1/20 0.38
GPX4 P36969 1/20 0.38
PAX8 Q06710 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NSD2 O96028 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13241985 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL13809080 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL12278998 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL12433905 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL12533862 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL15179066 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL17695178 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL2774865 0.96 HSD17B1 (0.43) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL14267126 0.96 HSD17B1 (0.43) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL19649023 0.96 HSD17B1 (0.43) HSD17B1HSD17B2ACHEALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180151624-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2018-05-31 US disclosed
US-20180151624-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2018-05-31 US disclosed