SCHEMBL12433905

SCHEMBL12433905

Cc1ccc(N(c2ccc(-c3ccc(N(c4ccc(C)cc4)c4cccc(C)c4)cc3)cc2)c2cccc(C)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 5/20 0.45
HSD17B2 P37059 5/20 0.45
ACHE P22303 3/20 0.42
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TP53 P04637 1/20 0.38
GPX4 P36969 1/20 0.38
PAX8 Q06710 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NSD2 O96028 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13241985 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL13809080 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL12278998 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL12533862 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL15179066 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL20201642 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL17695178 1.00 HSD17B1 (0.45) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL2774865 0.96 HSD17B1 (0.43) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL14267126 0.96 HSD17B1 (0.43) HSD17B1HSD17B2ACHEALDH1A1TSHR
SCHEMBL19649023 0.96 HSD17B1 (0.43) HSD17B1HSD17B2ACHEALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230059696-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-02-23 US disclosed
EP-3438752-B1 POSITIVELY CHARGEABLE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEM CORP (JP) 2022-01-12 EP disclosed
US-20190107790-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND COATING LIQUID FOR FORMING PHOTOSENSITIVE LAYER MITSUBISHI CHEMICAL CORPORATION (JP) 2019-04-11 US disclosed
EP-3438752-A1 POSITIVELY CHARGEABLE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS Mitsubishi Chemical Corporation (JP) 2019-02-06 EP disclosed
US-10197928-B2 Electrophotographic photoreceptor, image forming apparatus, and coating liquid for forming photosensitive layer MITSUBISHI CHEMICAL CORPORATION (JP) 2019-02-05 US disclosed
US-20190025719-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR FOR POSITIVE CHARGING, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2019-01-24 US disclosed
US-20170336724-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-11-23 US disclosed
US-20170336724-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-11-23 US disclosed
US-20170242353-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND COATING LIQUID FOR FORMING PHOTOSENSITIVE LAYER MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-24 US disclosed
US-20170242353-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND COATING LIQUID FOR FORMING PHOTOSENSITIVE LAYER MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-24 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-20120238774-A1 CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-7981581-B2 Halogenated phthalocyanine compounds; high sensitivity, small environmental dependence, only small fluctuations in electrical properties when the usage environment varies during repeated use MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-19 US disclosed
US-7981581-B2 Halogenated phthalocyanine compounds; high sensitivity, small environmental dependence, only small fluctuations in electrical properties when the usage environment varies during repeated use MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-19 US disclosed
US-20100232830-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-16 US disclosed
US-20100232830-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-16 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20080268357-A1 Phthalocyanine Composition and Photoconductive Material, Electrophotographic Photoreceptor Cartridge, and Image-Forming Apparatus Each Employing the Composition MITSUBISHI CHEMICAL CORPORATION (JP) 2008-10-30 US disclosed
US-20080268357-A1 Phthalocyanine Composition and Photoconductive Material, Electrophotographic Photoreceptor Cartridge, and Image-Forming Apparatus Each Employing the Composition MITSUBISHI CHEMICAL CORPORATION (JP) 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238774-A1 CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME PCTP, CDH1, PLTP HSD17B1 3941/4885HSD17B2 3654/4885ACHE 4539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.