Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 7/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20351534 | 0.80 | ACACB (0.36) | ACACB | |
| SCHEMBL20201713 | 0.76 | ACACB (0.40) | ACACB | |
| SCHEMBL20207823 | 0.72 | DUT (0.51) | DUTBACE1BACE2ACACB | |
| SCHEMBL21325417 | 0.70 | DUT (0.47) | DUT | |
| SCHEMBL22751576 | 0.69 | FFAR4 (0.35) | ACACB | |
| SCHEMBL20188388 | 0.69 | DUT (0.68) | DUT | |
| SCHEMBL29386565 | 0.69 | DUT (0.68) | DUT | |
| SCHEMBL20351400 | 0.69 | DUT (0.68) | DUT | |
| SCHEMBL18374243 | 0.69 | DUT (0.68) | DUT | |
| SCHEMBL18374246 | 0.68 | ACACB (0.43) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |