Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.40 |
| ▸ | ACACA | Q13085 | 5/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20351534 | 0.87 | ACACB (0.36) | ACACBACACAFFAR4PARP10PARP15 | |
| SCHEMBL18374246 | 0.83 | ACACB (0.43) | ACACBACACAFFAR4PARP10PARP15 | |
| SCHEMBL20374442 | 0.80 | PARP10 (0.45) | ACACBACACAFFAR4PARP10PARP15 | |
| SCHEMBL20207072 | 0.78 | PARP10 (0.48) | FFAR4PARP10PARP15FFAR1 | |
| SCHEMBL21350592 | 0.77 | CA1 (0.47) | ACACBACACAFFAR4PARP10PARP15 | |
| SCHEMBL20201675 | 0.76 | DUT (0.37) | ACACB | |
| SCHEMBL20338523 | 0.75 | ACACB (0.47) | ACACBACACAFFAR4PARP10PARP15 | |
| SCHEMBL20188183 | 0.75 | ACACB (0.47) | ACACBACACAFFAR4PARP10PARP15 | |
| SCHEMBL22751576 | 0.74 | FFAR4 (0.35) | ACACBFFAR4SCN1ASCN5ASCN8A | |
| SCHEMBL20338508 | 0.74 | DUT (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |