Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 5/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 6/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20189654 | 0.82 | DUT (0.70) | DUTGRM2 | |
| SCHEMBL21536582 | 0.76 | DUT (0.49) | DUTGRM2PDE4APDE4BPDE4C | |
| SCHEMBL24153550 | 0.74 | BACE1 (0.33) | DUTGRM2PDE4BGAA | |
| SCHEMBL18379994 | 0.73 | DUT (0.68) | DUTGRM2GAA | |
| SCHEMBL20189396 | 0.73 | DUT (0.49) | DUTGAA | |
| SCHEMBL21536743 | 0.71 | DUT (0.47) | DUTGRM2 | |
| SCHEMBL21536622 | 0.70 | DUT (0.47) | DUTGRM2 | |
| SCHEMBL21536091 | 0.70 | DUT (0.47) | DUTGRM2 | |
| SCHEMBL21536086 | 0.70 | DUT (0.47) | DUTGRM2 | |
| SCHEMBL21536094 | 0.70 | DUT (0.45) | DUTGRM2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |