Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | BRS3 | P32247 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536626 | 0.81 | CYP11B1 (0.44) | DUTDRD2 | |
| SCHEMBL21536693 | 0.74 | DUT (0.41) | PDE4BDUTDDB1CRBN | |
| SCHEMBL20201711 | 0.74 | DUT (0.47) | GAAGRM2PDE4BDUT | |
| SCHEMBL23996254 | 0.71 | KDM1A (0.42) | DRD2 | |
| SCHEMBL20189396 | 0.69 | DUT (0.49) | GAADUT | |
| SCHEMBL24154720 | 0.68 | GRM2 (0.30) | GRM2 | |
| SCHEMBL21536692 | 0.68 | HTR6 (0.46) | DUT | |
| SCHEMBL21536095 | 0.67 | DUT (0.46) | GRM2DUTDRD2ADRA1DSLC6A4 | |
| SCHEMBL21536743 | 0.67 | DUT (0.47) | GRM2DUTDDB1CRBN | |
| SCHEMBL21536086 | 0.67 | DUT (0.47) | GRM2DUTDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263205-A1 | COMBINATION THERAPY WITH DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-12-30 | — | — | WO | disclosed |