Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 18/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208013 | 1.00 | DUT (0.35) | DUTDDB1CRBN | |
| SCHEMBL20201870 | 0.90 | DUT (0.34) | DUT | |
| SCHEMBL20201716 | 0.87 | DUT (0.38) | DUTDDB1CRBN | |
| SCHEMBL18374451 | 0.86 | DUT (0.40) | DUT | |
| SCHEMBL20377820 | 0.86 | DUT (0.40) | DUT | |
| SCHEMBL20201841 | 0.86 | DUT (0.36) | DUTDDB1CRBN | |
| SCHEMBL18374229 | 0.84 | DUT (0.44) | DUT | |
| SCHEMBL18374484 | 0.84 | DUT (0.44) | DUT | |
| SCHEMBL18374039 | 0.84 | DUT (0.44) | DUT | |
| SCHEMBL18374036 | 0.82 | DUT (0.41) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |