SCHEMBL20201716

SCHEMBL20201716

O=C1CCC(CCCCCCCNC2(c3ccc(F)c(OCC4CC4)c3)CC2)C(=O)N1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DUT P33316 18/20 0.38
DDB1 Q16531 1/20 0.34
CRBN Q96SW2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20201869 0.90 DUT (0.36) DUT
SCHEMBL20201715 0.87 DUT (0.35) DUTDDB1CRBN
SCHEMBL20208013 0.87 DUT (0.35) DUTDDB1CRBN
SCHEMBL18374025 0.86 DUT (0.45) DUT
SCHEMBL22342443 0.86 DUT (0.45) DUT
SCHEMBL25053739 0.86 DUT (0.45) DUT
SCHEMBL22342444 0.86 DUT (0.45) DUT
SCHEMBL18374233 0.86 DUT (0.45) DUT
SCHEMBL18374467 0.84 DUT (0.43) DUT
SCHEMBL18374320 0.84 DUT (0.43) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018098206-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed