SCHEMBL20201844

SCHEMBL20201844

Brc1ccnc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MKNK1 Q9BUB5 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
EGFR P00533 2/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALDH1A1 P00352 2/20 0.34
ACHE P22303 1/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
ALK Q9UM73 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
GPR3 P46089 1/20 0.33
PDE4A P27815 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20296887 0.88 DDB1 (0.38) KDM4EATML3MBTL1MKNK1MKNK2
SCHEMBL30697391 0.85 HTT (0.43) KDM4EL3MBTL1EGFRMEN1KMT2A
SCHEMBL27024577 0.85 HTT (0.43) KDM4EL3MBTL1EGFRMEN1KMT2A
SCHEMBL29668112 0.82 SMN1; SMN2 (0.47) KDM4EL3MBTL1MKNK1MKNK2SMN1; SMN2
SCHEMBL12076977 0.82 SMN1; SMN2 (0.47) KDM4EL3MBTL1MKNK1MKNK2SMN1; SMN2
SCHEMBL34463244 0.81 COMT (0.38) KDM4EATML3MBTL1MKNK1MKNK2
SCHEMBL12077685 0.80 MEN1 (0.43) KDM4EATML3MBTL1SMN1; SMN2MEN1
SCHEMBL29668152 0.80 MEN1 (0.43) KDM4EATML3MBTL1SMN1; SMN2MEN1
SCHEMBL2730486 0.80 MEN1 (0.43) KDM4EATML3MBTL1SMN1; SMN2MEN1
SCHEMBL29853603 0.80 MEN1 (0.43) KDM4EATML3MBTL1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180151811-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180151811-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE OCIAD1, OCIAD2, AOX1 KDM4E 3243/4885ATM 3613/4885L3MBTL1 681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.