SCHEMBL2730486

SCHEMBL2730486

Brc1ccc2c(c1)c1ccccc1n2-c1ccccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
NPSR1 Q6W5P4 2/20 0.43
TSPO P30536 2/20 0.40
RAD52 P43351 1/20 0.39
POLB P06746 2/20 0.38
HRH1 P35367 1/20 0.38
HTR6 P50406 1/20 0.38
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 2/20 0.36
MAPK1 P28482 2/20 0.36
HSD17B10 Q99714 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
SLC11A2 P49281 1/20 0.36
TSHR P16473 2/20 0.36
ALOX15 P16050 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29853603 1.00 MEN1 (0.43) MEN1KMT2ANPSR1TSPORAD52
SCHEMBL28728317 0.95 MEN1 (0.43) MEN1KMT2ANPSR1POLBHRH1
SCHEMBL29668152 0.91 MEN1 (0.43) MEN1KMT2ANPSR1POLBRAB9A
SCHEMBL12077685 0.91 MEN1 (0.43) MEN1KMT2ANPSR1POLBRAB9A
SCHEMBL19533807 0.88 MEN1 (0.48) MEN1KMT2ANPSR1TSPOPOLB
SCHEMBL17105722 0.87 MEN1 (0.38) MEN1KMT2ANPSR1HRH1HTR6
SCHEMBL28009145 0.85 MEN1 (0.43) MEN1KMT2ANPSR1RAB9AALDH1A1
SCHEMBL20240126 0.85 MAT2A (0.43) MEN1KMT2ANPSR1POLBRAB9A
SCHEMBL10027578 0.85 POLB (0.43) MEN1KMT2ANPSR1POLBRAB9A
SCHEMBL730611 0.85 POLB (0.48) POLBRAB9AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114133381-A Synthesis method and application of nitrile-carbazole/pyridine bipolar host material 淮阴师范学院 2022-03-04 CN claimed
CN-114133381-A Synthesis method and application of nitrile-carbazole/pyridine bipolar host material 淮阴师范学院 2022-03-04 CN disclosed
US-9190623-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-11-17 US disclosed
US-9190623-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-11-17 US disclosed
US-9190623-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-11-17 US disclosed
WO-2015041428-A1 ORGANIC ELECTRONIC ELEMENT USING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2015-03-26 WO disclosed
WO-2015041428-A1 ORGANIC ELECTRONIC ELEMENT USING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2015-03-26 WO disclosed
US-20140138627-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-22 US disclosed
US-20140138627-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-22 US disclosed
US-20140138627-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-22 US disclosed
EP-2630140-A1 ORGANIC ELECTROLUMINESCENT DEVICE Commonwealth Scientific and Industrial Research Organisation (AU) 2013-08-28 EP disclosed
CN-103180313-A Organic electroluminescent device COMMW SCIENT IND RES ORG 2013-06-26 CN disclosed
US-20120261650-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-10-18 US disclosed
US-20120235123-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-09-20 US disclosed
US-20120235123-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-09-20 US disclosed
WO-2012051666-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-04-26 WO disclosed
WO-2011019156-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120235123-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME OCIAD1, OCIAD2, ODC1 MEN1 2625/4885KMT2A 2850/4885NPSR1 3459/4885
US-20120261650-A1 ORGANIC ELECTROLUMINESCENT DEVICE EBPL, PAICS, CCNL2 MEN1 4532/4885KMT2A 2532/4885NPSR1 4700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.