Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 5/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22751309 | 0.86 | CASR (0.36) | CASRLMNAALDH1A1SMN1; SMN2HSP90AA1 | |
| SCHEMBL11994358 | 0.85 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2BLMGAATRPA1 | |
| SCHEMBL6970183 | 0.78 | SMN1; SMN2 (0.44) | LMNAALDH1A1SMN1; SMN2IDO1TRPA1 | |
| SCHEMBL20207677 | 0.77 | SMN1; SMN2 (0.42) | LMNAALDH1A1SMN1; SMN2TRPA1MEN1 | |
| SCHEMBL25889572 | 0.76 | BCHE (0.37) | CASRBCHEACHELMNAALDH1A1 | |
| SCHEMBL22537648 | 0.76 | LMNA (0.38) | BCHEACHELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL21536701 | 0.76 | BACE1 (0.37) | — | |
| SCHEMBL20376237 | 0.75 | IDO1 (0.35) | ALDH1A1SMN1; SMN2IDO1GAATRPA1 | |
| SCHEMBL12963093 | 0.74 | EPHX1 (0.46) | CASRLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL21324923 | 0.72 | TRPV1 (0.38) | ALDH1A1IDO1HSP90AA1HSP90AB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |