Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 16/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21522628 | 0.80 | DUT (0.55) | DUT | |
| SCHEMBL20201689 | 0.80 | DUT (0.55) | DUT | |
| SCHEMBL20193328 | 0.72 | DUT (0.70) | DUT | |
| SCHEMBL18374225 | 0.72 | DUT (0.70) | DUT | |
| SCHEMBL20187705 | 0.72 | DUT (0.54) | DUT | |
| SCHEMBL31262777 | 0.72 | DUT (0.70) | DUT | |
| SCHEMBL20338520 | 0.71 | DUT (0.74) | DUT | |
| SCHEMBL31262711 | 0.71 | DUT (0.74) | DUT | |
| SCHEMBL18374021 | 0.71 | DUT (0.74) | DUT | |
| SCHEMBL20204810 | 0.70 | TLR4 (0.37) | DUTTLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |