Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 8/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568907 | 0.72 | TLR4 (0.50) | TLR4TLR2KMT2AACACBACACA | |
| SCHEMBL20204816 | 0.71 | TLR4 (0.47) | TLR4TLR2ACACBACACANR1H4 | |
| SCHEMBL20201901 | 0.70 | DUT (0.49) | TLR4TLR2DUT | |
| SCHEMBL4568816 | 0.69 | TLR4 (0.46) | TLR4TLR2 | |
| SCHEMBL25261825 | 0.69 | TLR4 (0.48) | TLR4TLR2 | |
| SCHEMBL25822083 | 0.69 | HTR1B (0.54) | TLR4TLR2ACACBACACA | |
| SCHEMBL4568801 | 0.67 | TLR4 (0.48) | TLR4TLR2KMT2A | |
| SCHEMBL4568813 | 0.67 | TLR4 (0.51) | TLR4TLR2KMT2A | |
| SCHEMBL25826082 | 0.67 | TLR4 (0.44) | TLR4TLR2 | |
| SCHEMBL4568768 | 0.66 | TLR4 (0.53) | TLR4TLR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |