Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | DUT | P33316 | 13/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201537 | 0.86 | DUT (0.51) | DUTACACB | |
| SCHEMBL20207754 | 0.86 | DUT (0.51) | DUTACACB | |
| SCHEMBL20373902 | 0.86 | SCN9A (0.43) | SCN9ADUT | |
| SCHEMBL18374371 | 0.84 | SCN9A (0.42) | SCN9ADUT | |
| Hydrochloric Acid SCHEMBL20191182 | 0.83 | SCN9A (0.41) | SCN9ADUT | |
| Hydrochloric Acid SCHEMBL20191183 | 0.83 | SCN9A (0.41) | SCN9ADUT | |
| SCHEMBL20370301 | 0.82 | SCN9A (0.38) | SCN9ADUTACACB | |
| SCHEMBL20201966 | 0.82 | CALM1 (0.37) | DUTACACB | |
| SCHEMBL21350275 | 0.79 | DUT (0.38) | SCN9ADUTACACB | |
| SCHEMBL12810253 | 0.78 | DUT (0.47) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |