Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SOD1 | P00441 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322457 | 0.84 | KDM4E (0.50) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL12075473 | 0.83 | MAPK1 (0.48) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL12075461 | 0.83 | MAPK1 (0.48) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL4164639 | 0.82 | HCRTR1 (0.42) | ALDH1A1MAPK1TSHRHCRTR1HCRTR2 | |
| SCHEMBL11162901 | 0.81 | GPBAR1 (0.50) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL9326234 | 0.81 | TAAR1 (0.53) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL9122825 | 0.81 | LMNA (0.59) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL9121963 | 0.81 | TSHR (0.48) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL19944724 | 0.81 | KDM4E (0.49) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL10289884 | 0.79 | KDM4E (0.53) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702422-B2 | Imidazopyridazines as modulators of IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-07-18 | — | — | US | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702422-B2 | Imidazopyridazines as modulators of IL-17 | IL17A, IL23R, IL15 | ALDH1A1 164/4885KDM4E 2583/4885MAPK1 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.