Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202023 | 0.86 | BACE1 (0.36) | PNPBACE1 | |
| SCHEMBL20202010 | 0.85 | PNP (0.36) | PNP | |
| SCHEMBL20202014 | 0.85 | PNP (0.37) | PNP | |
| SCHEMBL20206756 | 0.82 | PNP (0.39) | PNP | |
| SCHEMBL20206646 | 0.82 | PNP (0.36) | PNP | |
| SCHEMBL20202020 | 0.81 | PNP (0.38) | PNPKDM4E | |
| SCHEMBL20206657 | 0.80 | PNP (0.35) | PNP | |
| SCHEMBL20202017 | 0.79 | PNP (0.38) | PNP | |
| SCHEMBL20206650 | 0.77 | PNP (0.36) | PNP | |
| SCHEMBL20202021 | 0.77 | PNP (0.36) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148764-A1 | ENZYMATIC MODIFICATION OF NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-05-31 | — | — | US | disclosed |
| US-20180148764-A1 | ENZYMATIC MODIFICATION OF NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148764-A1 | ENZYMATIC MODIFICATION OF NUCLEIC ACIDS | RNGTT, UNG, RNASEL | PNP 41/4885KDM4E 1769/4885ALDH1A1 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.