Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202025 | 0.91 | TSHR (0.35) | TSHRSMN1; SMN2HTR2ANOTUMDRD2 | |
| SCHEMBL20202030 | 0.91 | TSHR (0.35) | TSHRSMN1; SMN2HTR2ANOTUMDRD2 | |
| SCHEMBL17084399 | 0.87 | SMN1; SMN2 (0.37) | TSHRSMN1; SMN2HPGDHTR2ANOTUM | |
| SCHEMBL20202032 | 0.84 | MAPT (0.38) | TSHRMEN1KMT2ALMNAKDM4E | |
| SCHEMBL17014960 | 0.81 | HTR2A (0.44) | HTR2ADRD2DRD1DRD4DRD3 | |
| SCHEMBL20202031 | 0.79 | MAPT (0.39) | TSHRMEN1KMT2ALMNAKDM4E | |
| SCHEMBL17084400 | 0.76 | ALDH1A1 (0.41) | TSHRSMN1; SMN2HPGDHTR2ADRD2 | |
| SCHEMBL17951855 | 0.75 | HPGD (0.48) | TSHRHPGDHTR2ANOTUMDRD2 | |
| SCHEMBL17084401 | 0.74 | TSHR (0.42) | TSHRSMN1; SMN2HPGDHTR2ADRD2 | |
| SCHEMBL6024750 | 0.72 | HPGD (0.47) | SMN1; SMN2HPGDHTR2ANOTUMDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148462-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148462-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | PKD1, ODC1, PIEZO1 | TSHR 4336/4885SMN1; SMN2 4515/4885HPGD 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.