SCHEMBL20202295

SCHEMBL20202295

C=C(C)C(=O)Oc1c(NC)cccc1NC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.42
KDM4E B2RXH2 3/20 0.41
ATM Q13315 2/20 0.41
POLB P06746 1/20 0.41
ALDH1A1 P00352 5/20 0.39
KMT2A Q03164 3/20 0.36
HPGD P15428 2/20 0.35
GAA P10253 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
RECQL P46063 1/20 0.33
TOP1 P11387 1/20 0.33
MEN1 O00255 1/20 0.33
EGFR P00533 1/20 0.33
MAPT P10636 1/20 0.33
PABPC1 P11940 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3838756 0.77 ELANE (0.47) ELANEKDM4EATMPOLBALDH1A1
SCHEMBL28836374 0.76 MAPT (0.43) ELANEKDM4EATMPOLBALDH1A1
SCHEMBL29092106 0.76 ALDH1A1 (0.53) ELANEKDM4EPOLBALDH1A1KMT2A
SCHEMBL10407840 0.76 ELANE (0.46) ELANEKDM4EATMALDH1A1KMT2A
SCHEMBL447625 0.76 ALDH1A1 (0.49) ELANEKDM4EATMALDH1A1KMT2A
SCHEMBL28412935 0.74 SMN1; SMN2 (0.42) KDM4EPOLBALDH1A1KMT2AHPGD
SCHEMBL8530339 0.74 ELANE (0.45) ELANEKDM4EATMALDH1A1KMT2A
SCHEMBL30227022 0.74 HTT (0.52) ELANEKDM4EPOLBALDH1A1KMT2A
SCHEMBL15302846 0.73 ELANE (0.51) ELANEKDM4EATMPOLBALDH1A1
SCHEMBL24804343 0.73 CA12 (0.46) ELANEKDM4EALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180157174-A1 NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2018-06-07 US disclosed
US-20180149975-A1 NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2018-05-31 US disclosed