Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraxetan SCHEMBL9995816 | 0.87 | HSD17B10 (0.48) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| Tetraxetan SCHEMBL4533056 | 0.82 | HSD17B10 (0.56) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| SCHEMBL9418242 | 0.80 | HSD17B10 (0.42) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| Tetraxetan SCHEMBL5370171 | 0.79 | HSD17B10 (0.58) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| Tetraxetan SCHEMBL18018 | 0.79 | HSD17B10 (0.64) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| SCHEMBL321989 | 0.79 | HSD17B10 (0.64) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| SCHEMBL173508 | 0.79 | HSD17B10 (0.64) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| SCHEMBL6848102 | 0.79 | HSD17B10 (0.64) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| Tetraxetan SCHEMBL2635294 | 0.79 | HSD17B10 (0.64) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 | |
| Tetraxetan SCHEMBL2017956 | 0.79 | HSD17B10 (0.64) | HSD17B10ALDH1A1STAT6SMN1; SMN2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098390-A1 | ALBUMIN-BINDING PSMA INHIBITORS | CANCER TARGETED TECHNOLOGY LLC (US) | 2018-05-31 | — | — | WO | disclosed |