SCHEMBL6848102

SCHEMBL6848102

O=C(O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.64
SLC6A9 P48067 1/20 0.47
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
STAT6 P42226 1/20 0.41
S1PR1 P21453 1/20 0.41
GAA P10253 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 1/20 0.38
CYP1A2 P05177 1/20 0.37
MAPK1 P28482 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173508 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL321989 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL3660521 1.00
Tetraxetan SCHEMBL2017956 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL18018 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL6744121 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL3503521 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL2635294 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL23647851 0.97 HSD17B10 (0.61) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL15766009 0.97 HSD17B10 (0.61) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4704924-A1 RADIONUCLIDE-LOADED NANOPARTICLES FOR FOCAL TISSUE ABLATION TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC (US) 2026-03-11 EP claimed
US-12329831-B2 Radionuclide-loaded nanoparticles for focal tissue ablation TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC (US) 2025-06-17 US claimed
WO-2024226199-A1 RADIONUCLIDE-LOADED NANOPARTICLES FOR FOCAL TISSUE ABLATION RAIKA MEDICAL IMAGING INC. (US) 2024-10-31 WO claimed
US-20240350684-A1 RADIONUCLIDE-LOADED NANOPARTICLES FOR FOCAL TISSUE ABLATION TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC 2024-10-24 US claimed
EP-4704924-A1 RADIONUCLIDE-LOADED NANOPARTICLES FOR FOCAL TISSUE ABLATION TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC (US) 2026-03-11 EP disclosed
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 EP disclosed
US-12329831-B2 Radionuclide-loaded nanoparticles for focal tissue ablation TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC (US) 2025-06-17 US disclosed
CN-119684401-A Compounds comprising a linker, a chelator, a ligand binding entity, methods of preparation and uses thereof 赛诺哈勃药业(成都)有限公司 2025-03-25 CN disclosed
WO-2024226199-A1 RADIONUCLIDE-LOADED NANOPARTICLES FOR FOCAL TISSUE ABLATION RAIKA MEDICAL IMAGING INC. (US) 2024-10-31 WO disclosed
EP-4455159-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS WITH BIO-DISTRIBUTION MODIFIER 3B Pharmaceuticals GmbH (DE) 2024-10-30 EP disclosed
US-20240350684-A1 RADIONUCLIDE-LOADED NANOPARTICLES FOR FOCAL TISSUE ABLATION TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC 2024-10-24 US disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
WO-2020186328-A1 CHELATORS AND METHODS OF MAKING AND USING SAME THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2020-09-24 WO disclosed
EP-3206720-B1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GMBH (DE) 2020-04-22 EP disclosed
US-20200061218-A1 Albumin-Binding PSMA Inhibitors CANCER TARGETED TECHNOLOGY LLC 2020-02-27 US disclosed
WO-2018098390-A1 ALBUMIN-BINDING PSMA INHIBITORS CANCER TARGETED TECHNOLOGY LLC (US) 2018-05-31 WO disclosed
US-20170327520-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GMBH (DE) 2017-11-16 US disclosed
WO-2016058704-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GMBH (DE) 2016-04-21 WO disclosed
US-6770020-B2 NEUTRON CAPTURE THERAPY (NCT) USING GADOLINIUM DIETHYLENETRIAMINEPENTAACETIC ACID; TREATING GLIOBLASTOMAS, GLIOMAS WISCONSIN ALUMNI RESEARCH FOUNDATION 2004-08-03 US disclosed
US-20030049202-A1 Method of using gadolinium neutron capture to treat cancers WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030049202-A1 Method of using gadolinium neutron capture to treat cancers NUCB2, MKI67, GMNN HSD17B10 3436/4885SLC6A9 620/4885ALDH1A1 4571/4885
US-20170327520-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES PTH1R, VDR, MEN1 HSD17B10 3937/4885SLC6A9 703/4885ALDH1A1 4006/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R HSD17B10 3848/4885SLC6A9 2603/4885ALDH1A1 3906/4885
US-20200061218-A1 Albumin-Binding PSMA Inhibitors PSMA1, ALB, PSMA2 HSD17B10 3053/4885SLC6A9 562/4885ALDH1A1 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.