SCHEMBL321989

SCHEMBL321989

O=C(O)CN1CCN(CC(=O)O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.64
SLC6A9 P48067 1/20 0.47
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
STAT6 P42226 1/20 0.41
S1PR1 P21453 1/20 0.41
GAA P10253 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 1/20 0.38
CYP1A2 P05177 1/20 0.37
MAPK1 P28482 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173508 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL3660521 1.00
Tetraxetan SCHEMBL2017956 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL6848102 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL18018 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL6744121 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL3503521 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL2635294 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL23647851 0.97 HSD17B10 (0.61) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL15766009 0.97 HSD17B10 (0.61) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6147183-A Amphoteric amine based polymers having a net cationic charge and process for their production BASF AKTIENGESELLSCHAFT (DE) 2000-11-14 US claimed
JP-61263962-A None JP disclosed
US-12503565-B2 Selective depolymerisation of polyamide 6 to produce caprolactam from mixtures of caprolactam-containing polymers and polyurethane-containing polymers, in particular polyurethane block copolymers BASF SE (DE) 2025-12-23 US disclosed
US-12453759-B2 Di-thioester cationic lipids TRANSLATE BIO, INC. (US) 2025-10-28 US disclosed
EP-4572884-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP General Electric Technology GmbH (CH) 2025-06-25 EP disclosed
CN-117946209-A Tumor targeting molecular probe and preparation method and application thereof 江西中医药大学 2024-04-30 CN disclosed
US-20240117142-A1 SELECTIVE DEPOLYMERISATION OF POLYAMIDE 6 TO PRODUCE CAPROLACTAM FROM MIXTURES OF CAPROLACTAM-CONTAINING POLYMERS AND POLYURETHANE-CONTAINING POLYMERS, IN PARTICULAR POLYURETHANE BLOCK COPOLYMERS BASF SE (DE) 2024-04-11 US disclosed
WO-2024039914-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2024-02-22 WO disclosed
EP-4263687-A1 SELECTIVE DEPOLYMERISATION OF POLYAMIDE 6 TO PRODUCE CAPROLACTAM FROM MIXTURES OF CAPROLACTAM-CONTAINING POLYMERS AND POLYURETHANE-CONTAINING POLYMERS, IN PARTICULAR POLYURETHANE BLOCK COPOLYMERS BASF SE (DE) 2023-10-25 EP disclosed
CN-116261581-A Selective depolymerization of polyamide 6 from a mixture of a caprolactam-containing polymer and a polyurethane-containing polymer, in particular a polyurethane block copolymer, to obtain caprolactam 巴斯夫欧洲公司 2023-06-13 CN disclosed
EP-0039226-B1 RESIN COMPOSITION COMPRISING WATER-SOLUBLE POLYAMIDE AND VINYL ALCOHOL-BASED POLYMER UNITIKA LTD. (JP) 1985-10-02 EP disclosed
US-4405705-A HYDROPHILIC TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) 1983-09-20 US disclosed
US-4365041-A LIGHT SENSITIVE, ADHESIVES UNITIKA LTD. (JP) 1982-12-21 US disclosed
EP-0039226-A2 Resin composition comprising water-soluble polyamide and vinyl alcohol-based polymer UNITIKA LTD. (JP) 1981-11-04 EP disclosed
US-4220704-A Water soluble photosensitive resin compositions comprising a polyamide or its salt TOYOBO CO., LTD. (JP) 1980-09-02 US disclosed
US-4218286-A Paper having good absorbency and alkali resistance and method of making said paper C. H. DEXTER LIMITED (GB) 1980-08-19 US disclosed
US-4188221-A REACTION PRODUCT OF (METH)ACRYLIC ACID AND A POLYGLYCIDYL ETHER OF A POLYOL, MOISTURE RESISTANCE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1980-02-12 US disclosed
US-4187112-A Photosensitive plate containing nitrogen containing condensation type polyesters TOYOBO CO., LTD. (JP) 1980-02-05 US disclosed
US-4145222-A Water soluble photosensitive resin composition comprising a polyamide or its ammonium salt TOYOBO CO., LTD. (JP) 1979-03-20 US disclosed
US-4096123-A COPOLYMER CONTAINING A TERTIARY AMINO GROUP TOYO BOSEKI KABUSHIKI KAISHA (JA) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12453759-B2 Di-thioester cationic lipids ACOT7, LYPLA2, LYPLA1 HSD17B10 584/4885SLC6A9 785/4885ALDH1A1 4370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.