SCHEMBL202027

SCHEMBL202027

CCCCCCCCCCCCCCSC

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
THRB P10828 2/20 0.53
CA2 P00918 1/20 0.46
TRPA1 O75762 3/20 0.42
HSD17B10 Q99714 2/20 0.42
CES2 O00748 1/20 0.42
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
GMNN O75496 1/20 0.42
TP53 P04637 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
BLM P54132 1/20 0.42
DNM1 Q05193 6/20 0.41
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200481 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10
SCHEMBL199323 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10
SCHEMBL200459 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10
SCHEMBL12749540 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10
SCHEMBL200935 1.00
SCHEMBL22214867 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10
SCHEMBL387242 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10
SCHEMBL198940 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10
SCHEMBL198830 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10
SCHEMBL200493 1.00 TSHR (0.53) TSHRTHRBCA2TRPA1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. 2024-07-04 US disclosed
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-06-27 US disclosed
US-20230338411-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS RECODE THERAPEUTICS, INC. 2023-10-26 US disclosed
CN-110462502-B Method for manufacturing liquid crystal element JSR株式会社 2022-05-17 CN disclosed
CN-111718728-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element JSR株式会社 2020-09-29 CN disclosed
EP-3331895-B1 PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF USEFUL AS ANTIVIRAL AGENTS CHIMERIX INC (US) 2020-07-29 EP disclosed
US-20170037399-A1 CHIRAL DESIGN WAVE LIFE SCIENCES LTD. (SG) 2017-02-09 US disclosed
US-20150211006-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2015-07-30 US disclosed
US-8481736-B2 Liquid crystalline rylene tetracarboxylic acid derivatives and use thereof BASF SE (DE) 2013-07-09 US disclosed
US-8088922-B2 Dibenzorylenetetracarboximides as infrared absorbers BASF AKTIENGESELLSCHAFT (DE) 2012-01-03 US disclosed
WO-2007138051-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2007-12-06 WO disclosed
WO-2007116001-A2 LIQUID CRYSTALLINE RYLENE TETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF BASF SE (DE) 2007-10-18 WO disclosed
EP-1843407-A1 Liquid crystalline rylenetetracarboxylic acid derivatives and their use BASF AKTIENGESELLSCHAFT (DE) 2007-10-10 EP disclosed
EP-0691327-B1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME KAO CORP (JP) 1999-07-21 EP disclosed
US-5723497-A AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE KAO CORPORATION (JP) 1998-03-03 US disclosed
EP-0691327-A1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME Kao Corporation (JP) 1996-01-10 EP disclosed
EP-0064441-B1 BIOCIDAL COMPOSITION BASED ON SULFONIUM SALTS AND ORGANO TIN COMPOUNDS SOCIETE NATIONALE ELF AQUITAINE (FR) 1984-09-26 EP disclosed
US-4166038-A OIL RECOVERY MOBIL OIL CORPORATION (US) 1979-08-28 US disclosed
US-4060495-A GERMICIDAL DETERGENT LEVER BROTHERS COMPANY (US) 1977-11-29 US disclosed
US-4034046-A GERMICIDES LEVER BROTHERS COMPANY (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS CHMP4B, LIPA, NPC1L1 TSHR 2262/4885THRB 2609/4885CA2 1829/4885
US-20150211006-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 TSHR 3259/4885THRB 2995/4885CA2 904/4885
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, NPC1L1, NPC1 TSHR 3323/4885THRB 4690/4885CA2 4324/4885
US-20230338411-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS CHMP4B, LIPA, NPC1L1 TSHR 2262/4885THRB 2609/4885CA2 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.