Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 12/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18272444 | 1.00 | SLC9A1 (0.47) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL22654473 | 0.85 | KDM1A (0.57) | SLC9A1KDM1A | |
| SCHEMBL248385 | 0.84 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL12915852 | 0.84 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL29488083 | 0.84 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL15196464 | 0.84 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL7655989 | 0.84 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL18272446 | 0.84 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL247915 | 0.84 | SLC9A1 (0.48) | SLC9A1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL248384 | 0.84 | FFAR1 (0.50) | SLC9A1HTR2AHTR2CHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148745-A1 | HEMOPROTEIN CATALYSTS FOR IMPROVED ENANTIOSELECTIVE ENZYMATIC SYNTHESIS OF TICAGRELOR | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-05-31 | — | — | US | disclosed |