SCHEMBL20202926

SCHEMBL20202926

CCCCCc1ccc(-c2ccc(-c3ccc4c(F)c(F)c(F)cc4c3)c(F)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 0.49
RARA P10276 2/20 0.49
RARG P13631 1/20 0.49
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
MTOR P42345 1/20 0.37
KMT2A Q03164 1/20 0.37
HTR2A P28223 1/20 0.37
MPL P40238 5/20 0.36
HRH3 Q9Y5N1 1/20 0.36
DHODH Q02127 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202925 0.96 RARB (0.44) RARBRARARARGTSHRMPL
SCHEMBL20202924 0.93 RARB (0.48) RARBRARARARGTSHRHSD17B10
SCHEMBL16210613 0.91 RARB (0.38) RARBRARARARGHSD17B10MPL
SCHEMBL20202923 0.89 RARB (0.43) RARBRARARARGTSHRMPL
SCHEMBL17075759 0.87 RARB (0.41) RARBRARARARGHSD17B10MPL
SCHEMBL15088582 0.87 HSD17B1 (0.37) RARBRARARARG
SCHEMBL20202961 0.86 RARB (0.42) RARBRARARARGTSHRHSD17B10
SCHEMBL16258051 0.86 RARB (0.57) RARBRARARARGTSHRHSD17B10
SCHEMBL3162066 0.85 RARB (0.43) RARBRARARARGTSHRHSD17B10
SCHEMBL20202930 0.84 RARB (0.42) RARBRARARARGMAPTMPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed