SCHEMBL20202925

SCHEMBL20202925

CCCCc1ccc(-c2ccc(-c3ccc4c(F)c(F)c(F)cc4c3)c(F)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.44
RARA P10276 1/20 0.44
RARG P13631 1/20 0.44
MPL P40238 15/20 0.39
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202926 0.96 RARB (0.49) RARBRARARARGMPLTSHR
SCHEMBL20202923 0.92 RARB (0.43) RARBRARARARGMPLNPC1
SCHEMBL16210613 0.92 RARB (0.38) RARBRARARARGMPLNPC1
SCHEMBL20202924 0.89 RARB (0.48) RARBRARARARGMPLTSHR
SCHEMBL17075759 0.88 RARB (0.41) RARBRARARARGMPLNPC1
SCHEMBL15088582 0.88 HSD17B1 (0.37) RARBRARARARG
SCHEMBL20202964 0.86 RARB (0.38) RARBRARARARGMPL
SCHEMBL16258024 0.85 RARB (0.51) RARBRARARARGMPLTSHR
SCHEMBL3158642 0.84 RARB (0.39) RARBRARARARGMPL
SCHEMBL13116412 0.84 ALOX5 (0.40) RARBMPLNPC1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed