SCHEMBL20202945

SCHEMBL20202945

CCCCCc1cc(F)c(C(F)(F)Oc2ccc(-c3ccc4c(F)c(F)c(F)cc4c3)cc2)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.37
RARA P10276 2/20 0.37
RARG P13631 1/20 0.37
GSK3B P49841 1/20 0.32
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
FAAH O00519 1/20 0.30
SCN9A Q15858 1/20 0.30
S1PR1 P21453 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202935 0.97 GSK3B (0.33) RARBRARARARGGSK3B
SCHEMBL20202941 0.92 GSK3B (0.34) GSK3B
SCHEMBL20202928 0.90 GSK3B (0.33) GSK3B
SCHEMBL20202932 0.90 RARB (0.37) RARBRARARARGFAAHS1PR1
SCHEMBL20202965 0.90 RARB (0.40) RARBRARARARGMAPTRAB9A
SCHEMBL20202948 0.90 RARB (0.40) RARBRARARARGMAPTRAB9A
SCHEMBL20202969 0.87 RARB (0.39) RARBRARARARGFAAHS1PR1
SCHEMBL20202933 0.87 ALOX5AP (0.36) RARBS1PR1
SCHEMBL17075778 0.87 ALOX5AP (0.34) GSK3B
SCHEMBL7735200 0.87 RARB (0.41) RARBRARARARGMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed