SCHEMBL20202928

SCHEMBL20202928

CCc1cc(F)c(C(F)(F)Oc2ccc(-c3ccc4c(F)c(F)c(F)cc4c3)cc2)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
PRMT6 Q96LA8 1/20 0.32
SERPINE1 P05121 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202941 0.93 GSK3B (0.34) GSK3BPRMT6
SCHEMBL20202935 0.91 GSK3B (0.33) GSK3B
SCHEMBL20202945 0.90 RARB (0.37) GSK3B
SCHEMBL20202946 0.89 ALOX5AP (0.39) ESR1ESR2
SCHEMBL17075778 0.87 ALOX5AP (0.34) GSK3B
SCHEMBL20202959 0.87 PPM1A (0.30)
SCHEMBL20202967 0.87 PPM1A (0.30)
SCHEMBL7732941 0.85 PRMT6 (0.35) PRMT6
SCHEMBL20202968 0.85 ALOX5AP (0.35)
SCHEMBL20202931 0.82 ALOX5AP (0.38) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed