Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | IL5 | P05113 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016715 | 1.00 | NR3C1 (0.71) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL12574247 | 0.92 | NR3C1 (0.61) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL2018429 | 0.91 | NR3C1 (0.73) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL2023082 | 0.91 | NR3C1 (0.73) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL12574239 | 0.90 | NR3C1 (0.78) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL2016820 | 0.90 | NR3C1 (0.78) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL2014959 | 0.89 | NR3C1 (0.69) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL12574221 | 0.89 | NR3C1 (0.69) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL12574237 | 0.89 | NR3C1 (0.67) | NR3C1CYP3A4HIF1AABCC3ABCC4 | |
| SCHEMBL12574216 | 0.88 | NR3C1 (0.68) | NR3C1CYP3A4HIF1AABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160167-A1 | Steroid Derivatives Acting As Glucocorticosteroid Receptor Agonists | ASTRAZENECA AB (SE) | 2011-06-30 | — | — | US | disclosed |
| US-20110160167-A1 | Steroid Derivatives Acting As Glucocorticosteroid Receptor Agonists | ASTRAZENECA AB (SE) | 2011-06-30 | — | — | US | disclosed |
| US-20110160167-A1 | Steroid Derivatives Acting As Glucocorticosteroid Receptor Agonists | ASTRAZENECA AB (SE) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160167-A1 | Steroid Derivatives Acting As Glucocorticosteroid Receptor Agonists | NR3C1, NR3C2, MC2R | NR3C1 1/4885CYP3A4 360/4885HIF1A 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.